Microsoft and Purdue Unlock the Future of Topological Qubits

Tyler Lindemann, a researcher in the Microsoft Quantum Lab West Lafayette and a Purdue University doctoral student, uses a molecular beam epitaxy system to create hybrid superconductor-semiconductor structures. Credit: Purdue University photo/Charles Jischke

Microsoft Quantum and Purdue University researchers have made a major leap in quantum computing, publishing a paper in Nature detailing how they successfully measured a key property of topological qubits.

Their work pushes semiconductor-superconductor hybrid technology to new heights and strengthens Purdue’s role in quantum research.

Microsoft Advances Topological Quantum Computing

Microsoft Quantum recently published an article in Nature, highlighting key advancements in measuring quantum devices — an essential step toward building a topological quantum computer. The research was conducted by Microsoft scientists and engineers, including those at Microsoft Quantum Lab West Lafayette, based at Purdue University. In their announcement, the team described the operation of a crucial device that serves as a foundational building block for topological quantum computing. Their findings mark a significant milestone in the development of quantum computers, which have the potential to be far more powerful and resilient than current technologies.

“Our hope for quantum computation is that it will aid chemists, materials scientists and engineers working on the design and manufacturing of new materials that are so important to our daily lives,” said Michael Manfra, scientific director of Microsoft Quantum Lab West Lafayette and the Bill and Dee O’Brien Distinguished Professor of Physics and Astronomy, professor of materials engineering, and professor of electrical and computer engineering at Purdue. “The promise of quantum computation is in accelerating scientific discovery and its translation into useful technology. For example, if quantum computers reduce the time and cost to produce new lifesaving therapeutic drugs, that is real societal impact.”

Majorana 1 Topological Quantum Processor — Majorana 1, the eight-qubit topological quantum processor unveiled at Microsoft Station Q’s 2025 conference. Credit: Microsoft

Building the Quantum Plane with Precision

The Microsoft Quantum Lab West Lafayette team advanced the complex layered materials that make up the quantum plane of the full device architecture used in the tests. Microsoft scientists working with Manfra are experts in advanced semiconductor growth techniques, including molecular beam epitaxy, that are used to build low-dimensional electron systems that form the basis for quantum bits, or qubits. They built the semiconductor and superconductor layers with atomic layer precision, tailoring the material’s properties to those needed for the device architecture.

Manfra, a member of the Purdue Quantum Science and Engineering Institute, credited the strong relationship between Purdue and Microsoft, built over the course of a decade, with the advances conducted at Microsoft Quantum Lab West Lafayette. In 2017 Purdue deepened its relationship with Microsoft with a multiyear agreement that includes embedding Microsoft employees with Manfra’s research team at Purdue.

A Breakthrough in Quantum Measurement

“This was a collaborative effort by a very sophisticated team, with a vital contribution from the Microsoft scientists at Purdue,” Manfra said. “It’s a Microsoft team achievement, but it’s also the culmination of a long-standing partnership between Purdue and Microsoft. It wouldn’t have been possible without an environment at Purdue that was conducive to this mode of work — I attempted to blend industrial with academic research to the betterment of both communities. I think that’s a success story.”

Quantum science and engineering at Purdue is a pillar of the Purdue Computes initiative, which is focused on advancing research in computing, physical AI, semiconductors and quantum technologies.

“This research breakthrough in the measurement of the state of quasi particles is a milestone in the development of topological quantum computing, and creates a watershed moment in the semiconductor-superconductor hybrid structure,” Purdue President Mung Chiang said. “Marking also the latest success in the strategic initiative of Purdue Computes, the deep collaboration that Professor Manfra and his team have created with the Microsoft Quantum Lab West Lafayette on the Purdue campus exemplifies the most impactful industry research partnership at any American university today.”

Why Topological Quantum Computing is Different

Most quantum computers encode information using local properties, such as the spin of an electron, to create qubits. However, these qubits are highly sensitive to external factors like heat, vibrations, and interactions with other quantum particles, making them prone to errors that require complex correction techniques.

Topological quantum computers take a different approach by distributing information across multiple particles that work together. This makes the qubit state much more stable, as altering it requires changing the state of all the particles involved. As a result, topological qubits are more resistant to disturbances, offering a more robust foundation for quantum computing.

In the Nature paper, the Microsoft team was able to accurately and quickly measure the state of quasi particles that form the basis of the qubit.

“The device is used to measure a basic property of a topological qubit quickly,” Manfra said. “The team is excited to build on these positive results.”

Pushing Semiconductor-Superconductor Technology Further

“The team in West Lafayette pushed existing epitaxial technology to a new state-of-the-art for semiconductor-superconductor hybrid structures to ensure a perfect interface between each of the building blocks of the Microsoft hybrid system,” said Sergei Gronin, a Microsoft Quantum Lab scientist.

“The materials quality that is required for quantum computing chips necessitates constant improvements, so that’s one of the biggest challenges,” Gronin said. “First, we had to adjust and improve semiconductor technology to meet a new level that nobody was able to achieve before. But equally important was how to create this hybrid system. To do that, we had to merge a semiconducting part and a superconducting part. And that means you need to perfect the semiconductor and the superconductor and perfect the interface between them.”

A Unique Opportunity for Purdue Students

While work discussed in the Nature article was performed by Microsoft employees, the exposure to industrial-scale research and development is an outstanding opportunity for Purdue students in Manfra’s academic group as well. John Watson, Geoffrey Gardner and Saeed Fallahi, who are among the coauthors of the paper, earned their doctoral degrees under Manfra and now work for Microsoft Quantum at locations in Redmond, Washington, and Copenhagen, Denmark. Most of Manfra’s former students now work for quantum computing companies, including Microsoft. Tyler Lindemann, who works in the West Lafayette lab and helped to build the hybrid semiconductor-superconductor structures required for the device, is earning a doctoral degree from Purdue under Manfra’s supervision.

“Working in Professor Manfra’s lab in conjunction with my work for Microsoft Quantum has given me a head start in my professional development, and been fruitful for my academic work,” Lindemann said. “At the same time, many of the world-class scientists and engineers at Microsoft Quantum have some background in academia, and being able to draw from their knowledge and experience is an indispensable resource in my graduate studies. From both perspectives, it’s a great opportunity.”

Explore Further: A New State of Matter Just Changed the Future of Quantum Computing

Reference: “Interferometric single-shot parity measurement in InAs–Al hybrid devices” by Microsoft Azure Quantum, Morteza Aghaee, Alejandro Alcaraz Ramirez, Zulfi Alam, Rizwan Ali, Mariusz Andrzejczuk, Andrey Antipov, Mikhail Astafev, Amin Barzegar, Bela Bauer, Jonathan Becker, Umesh Kumar Bhaskar, Alex Bocharov, Srini Boddapati, David Bohn, Jouri Bommer, Leo Bourdet, Arnaud Bousquet, Samuel Boutin, Lucas Casparis, Benjamin J. Chapman, Sohail Chatoor, Anna Wulff Christensen, Cassandra Chua, Patrick Codd, William Cole, Paul Cooper, Fabiano Corsetti, Ajuan Cui, Paolo Dalpasso, Juan Pablo Dehollain, Gijs de Lange, Michiel de Moor, Andreas Ekefjärd, Tareq El Dandachi, Juan Carlos Estrada Saldaña, Saeed Fallahi, Luca Galletti, Geoff Gardner, Deshan Govender, Flavio Griggio, Ruben Grigoryan, Sebastian Grijalva, Sergei Gronin, Jan Gukelberger, Marzie Hamdast, Firas Hamze, Esben Bork Hansen, Sebastian Heedt, Zahra Heidarnia, Jesús Herranz Zamorano, Samantha Ho, Laurens Holgaard, John Hornibrook, Jinnapat Indrapiromkul, Henrik Ingerslev, Lovro Ivancevic, Thomas Jensen, Jaspreet Jhoja, Jeffrey Jones, Konstantin V. Kalashnikov, Ray Kallaher, Rachpon Kalra, Farhad Karimi, Torsten Karzig, Evelyn King, Maren Elisabeth Kloster, Christina Knapp, Dariusz Kocon, Jonne V. Koski, Pasi Kostamo, Mahesh Kumar, Tom Laeven, Thorvald Larsen, Jason Lee, Kyunghoon Lee, Grant Leum, Kongyi Li, Tyler Lindemann, Matthew Looij, Julie Love, Marijn Lucas, Roman Lutchyn, Morten Hannibal Madsen, Nash Madulid, Albert Malmros, Michael Manfra, Devashish Mantri, Signe Brynold Markussen, Esteban Martinez, Marco Mattila, Robert McNeil, Antonio B. Mei, Ryan V. Mishmash, Gopakumar Mohandas, Christian Mollgaard, Trevor Morgan, George Moussa, Chetan Nayak, Jens Hedegaard Nielsen, Jens Munk Nielsen, William Hvidtfelt Padkar Nielsen, Bas Nijholt, Mike Nystrom, Eoin O’Farrell, Thomas Ohki, Keita Otani, Brian Paquelet Wütz, Sebastian Pauka, Karl Petersson, Luca Petit, Dima Pikulin, Guen Prawiroatmodjo, Frank Preiss, Eduardo Puchol Morejon, Mohana Rajpalke, Craig Ranta, Katrine Rasmussen, David Razmadze, Outi Reentila, David J. Reilly, Yuan Ren, Ken Reneris, Richard Rouse, Ivan Sadovskyy, Lauri Sainiemi, Irene Sanlorenzo, Emma Schmidgall, Cristina Sfiligoj, Mustafeez Bashir Shah, Kevin Simoes, Shilpi Singh, Sarat Sinha, Thomas Soerensen, Patrick Sohr, Tomas Stankevic, Lieuwe Stek, Eric Stuppard, Henri Suominen, Judith Suter, Sam Teicher, Nivetha Thiyagarajah, Raj Tholapi, Mason Thomas, Emily Toomey, Josh Tracy, Michelle Turley, Shivendra Upadhyay, Ivan Urban, Kevin Van Hoogdalem, David J. Van Woerkom, Dmitrii V. Viazmitinov, Dominik Vogel, John Watson, Alex Webster, Joseph Weston, Georg W. Winkler, Di Xu, Chung Kai Yang, Emrah Yucelen, Roland Zeisel, Guoji Zheng and Justin Zilke, 19 February 2025, Nature.
DOI: 10.1038/s41586-024-08445-2